Hydrazine → HCID 86705563, compound

Participants

Reaction Steps

To a solution of 296 (4.71 g, 10.5 mmol) in MeOH was added hydrazine (0.336 g, 10.5 mmol) and the reaction was stirred at RT overnight. The thick white suspension was taken up in hot MeOH, sonicated, filtered and washed with MeOH. The filtrate was concentrated to afford 2.98 g (89%) of tert-butyl 3-amino-3-(3,4-dichlorophenyl)propylcarbamate (298) as a pale yellow foam: LRMS (APCI pos) m/e=319.0 (M+H).

Provenance & Evidence