HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexyl isocyanide → [8-Benzyloxy-2-(3,5-dimethoxyphenyl)-imidazo[1,2-a]pyridin-3-yl]-cyclohexylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexyl isocyanide | HCID 79129 | — |
| Reactant | 3,5-Dimethoxybenzaldehyde | HCID 81747 | — |
| Reactant | 2-Amino-3-benzyloxypyridine | HCID 90334 | — |
| Solvent | Perchloric Acid | HCID 24247 | — |
| Product | [8-Benzyloxy-2-(3,5-dimethoxyphenyl)-imidazo[1,2-a]pyridin-3-yl]-cyclohexylamine | HCID 9911979 | — |
Reaction Steps
Compound (10) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-3-benzyloxypyridine solution (0.1 M, DCM), 0.575 ml of cyclohexyl isocyanide solution (0.2 M, DCM), 0.500 ml of 3,5-dimethoxybenzaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06849642B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-989a97d5a8f2419da7256687cc0f15d0 |
| Source note | uspto-grants-2005_02 |