HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexylamine → HCID 68842668, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexylamine | HCID 8102 | — |
| Reactant | (2S,4S)-1-[(N-benzyloxycarbonyl-N-[4-(benzotriazol-1-yl)oxycarbonylbicyclo[2.2.2]oct-1-yl]amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile | HCID 57756828 | — |
| Product | HCID 68842668 | HCID 68842668 | — |
Reaction Steps
In a similar manner to Example 4, (2S,4S)-1-[[N-benzyloxycarbonyl-N-[4-(benzotriazol-1-yl)oxycarbonylbicyclo[2.2.2]oct-1-yl]amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (50.0 mg) and hexylamine (15.0 μL) were used to obtain (2S,4S)-1-[[N-benzyloxycarbonyl-N-[4-(N-hexylamino)carbonylbicyclo[2.2.2]oct-1-yl]amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (42.7 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560569B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-286d7aa70d9e40b99fd953e3c0cc95e6 |
| Source note | uspto-grants-2009_07 |