HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67278842, compound → HCID 58916222, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67278842 | HCID 67278842 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | HCID 58916222 | HCID 58916222 | — |
Reaction Steps
In analogy to example 3 step 5 with 22 mg succinic acid 4-{4-[(5S)-5-(acetylamino-methyl)-2-oxo-oxazolidin-3-yl]-2-fluoro-phenoxymethyl}-1-(6-carboxy-8-cyclopropyl-3-fluoro-5-oxo-5,8-dihydro-[1,8]naphthyridin-2-yl)-piperidin-4-yl ester benzyl ester (MW: 817.80, 0.026 mmol) and 2 mg of palladium hydroxide 20% on activated carbon in 20 ml of a 1/1 tetrahydrofuran/methanol mixture. Yield: 16 mg, 81%. MS: 729 (M+H)+, 727 (M+H)−, Method ESI+, ESI−.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133213B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-0a0dd3aaa89c4e0ca6a511d98937cfbc |
| Source note | uspto-grants-2015_09 |