4,4'-Dimethoxybenzil → 4,4'-Dihydroxybenzil

Participants

Reaction Steps

12 g of anisil was dissolved in 120 ml of acetic acid and 240 ml of 48% hydrobromic acid. The mixture was stirred vigorously and heated to reflux to for 4 hours. The temperature was then lowered to 90° C. and left overnight. The resulting solution was poured over ice and the precipitate was collected by filtration and washed with water. After drying, 10.43 g of product (yield: 75.0 mol %) with a purity of 76.8% was obtained. The purity was measured by gas chromatography.

Provenance & Evidence