HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine → 2-Amino-5-bromo-N-ethylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | 2-Amino-5-bromo-N,N-diethylbenzamide | HCID 50999513 | — |
| Product | 2-Amino-5-bromo-N-ethylbenzamide | HCID 18711856 | 70% |
Reaction Steps
Prepared analogously to Compound 3D replacing diethylamine with ethylamine to afford 1.41 g of the title product (70%). 1H NMR (400 MHz, CD3OD) δ 7.55 (d, J=2.3 Hz, 1H), 7.25 (dd, J=2.4, 8.7 Hz, 1H), 6.67 (d, J=8.8 Hz, 1H), 3.32-3.38 (m, 2H), 1.20 (t, J=7.3 Hz, 3H). MS (ESI): m/z 243.33 [M+H]+. UPLC: tR=0.98 min (UPLC-SQD: analytical—2 min).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133224B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-ee61a3792c1e4a2ba089437064b13829 |
| Source note | uspto-grants-2015_09 |