HRID2279790
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
Prepared analogously to Compound 1B replacing Compound C with 6-amino-3-[1-(3-hydroxypropyl)-1H-pyrazol-4-yl]-N,2-dimethyl benzamide (Compound 29C). 1H NMR (CD3OD, 400 MHz): δ=8.28 (s, 1H), 7.92 (s, 1H), 7.89 (d, J=8.3 Hz, 1H), 7.72 (s, 1H), 7.63 (d, J=8.4 Hz, 1H), 7.48 (d, J=8.3 Hz, 1H), 6.92 (t, J=2.0 Hz, 1H), 6.60 (d, J=7.4 Hz, 1H), 4.35 (t, J=6.8 Hz, 2H), 4.00 (m, 4H), 3.89 (s, 3H), 3.60 (t, J=6.1 Hz, 2H), 3.16 (d, J=21.5 Hz, 2H), 2.85 (s, 3H), 2.37 (s, 3H), 2.12 (m, 2H), 1.22 (t, J=7.1 Hz, 6H). MS (ESI): m/z=706.58 [M+H]+. HPLC: tR=3.47 min (ZQ3: polar—5 min).
WORKUP
后处理
- customHPLC: tR=3.47 min (ZQ3: polar—5 min)