HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-6-methoxybenzoic Acid → 5-Methoxy-2H-3,1-benzoxazine-2,4(1H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-6-methoxybenzoic Acid | HCID 2735357 | — |
| Reactant | 6-Fluoroisatoic anhydride | HCID 2783057 | — |
| Product | 5-Methoxy-2H-3,1-benzoxazine-2,4(1H)-dione | HCID 10750295 | — |
Reaction Steps
Prepared analogously to Compound 27E replacing 2-amino-6-fluorobenzoic acid with 2-amino-6-methoxybenzoic acid. 1H NMR (DMSO-d6, 500 MHz) δ 3.87 (s, 3H), 6.64 (d, J=8.6 Hz, 1H), 6.81 (d, J=8.6 Hz, 1H), 7.65 (m, 1H), 11.59 (br.s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133224B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-bdf30d15f6264a48930e0ddc1ae200f0 |
| Source note | uspto-grants-2015_09 |