HCID 67818204, compound → HCID 67819081, compound

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Reaction Steps

Prepared analogously to Compound 34C replacing Compound 34D with 3-amino-6-{1-[3-(benzyloxy)propyl]-5-methyl-1H-pyrazol-4-yl}-N-methylpyridine-2-carboxamide (Compound 34E, 429 mg, 1.13 mmol) to afford 177 mg of the title compound (54%). 1H NMR (400 MHz, CD3OD) δ 7.75 (s, 1H), 7.35 (d, J=8.8 Hz, 1H), 7.12 (d, J=8.6 Hz, 1H), 4.18 (t, J=7.1 Hz, 2H), 3.51 (t, J=6.2 Hz, 2H), 2.89 (s, 3H), 2.51 (s, 3H), 1.97 (quin, J=6.6 Hz, 2H). MS (ESI): m/z=290.57 [M+H]+. UPLC: tR=0.67 min (UPLC-SQD: analytical—2 min).

Provenance & Evidence