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HRID2279826

反应详情

EQUATION

反应方程式

HRID 2279826 的结构方程式

REACTANTS

反应物

2
结构：Cc1nn(CCCOCc2ccccc2)c(C)c1B1OC(C)(C)C(C)(C)O1
HCID67812175

未命名化合物

2 次

结构：CCOP(=O)(O)Cc1ccc(Nc2ncc(C(F)(F)F)c(Nc3ccc(-c4cc(C(=O)OC)n(CCCO)c4)nc3C(=O)NC)n2)c(OC)c1
HCID86697760

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nn(CCCO)c(C)c1B1OC(C)(C)C(C)(C)O1
HCID67813938

未命名化合物

收率 100.2%

PROCEDURE

实验过程

1-[3-(Benzyloxy)propyl]-3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (Compound 43C, 560 mg, 1.5 mmol) was hydrogenated using the procedure from Compound 38A to afford 421 mg of the desired title compound (99%). 1H NMR (400 MHz, CD3OD) δ 4.08 (t, J=7.1 Hz, 2H), 3.50 (t, J=6.1 Hz, 2H), 2.40 (s, 3H), 2.27 (s, 3H), 1.95 (t, J=6.7 Hz, 2H), 1.30 (s, 12H). MS (ESI): m/z=280.37 [M+H]+. UPLC: tR=1.29 min (UPLC-TOF: polar—2 min).