HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxybenzaldehyde → 6-bromo-2-(2-methoxyphenyl)-N-(2,4,4-trimethylpentan-2-yl)imidazo[1,2-a]pyridin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxybenzaldehyde | HCID 8658 | — |
| Reactant | 1,1,3,3-Tetramethylbutyl isocyanide | HCID 26725 | — |
| Reactant | 2-Amino-5-bromopyridine | HCID 70622 | — |
| Solvent | Perchloric Acid | HCID 24247 | — |
| Product | 6-bromo-2-(2-methoxyphenyl)-N-(2,4,4-trimethylpentan-2-yl)imidazo[1,2-a]pyridin-3-amine | HCID 3532132 | — |
Reaction Steps
Compound (13) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-5-bromopyridine solution (0.1 M, DCM), 0.575 ml of 1,1,3,3-tetramethylbutyl isocyanide solution (0.2 M, DCM), 0.500 ml of 2-methoxybenzaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06849642B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-fd9e70201c864437b2080fdccf512e23 |
| Source note | uspto-grants-2005_02 |