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HRID2279918

反应详情

EQUATION

反应方程式

HRID 2279918 的结构方程式

REACTANTS

反应物

2
结构：CCO[PH](=O)CCCCc1ccc(Nc2ncc(C(F)(F)F)c(Nc3ccc(Br)nc3C(=O)NC)n2)c(OC)c1
HCID178476807

未命名化合物

2 次

结构：CNC(=O)c1nc(Br)ccc1Nc1nc(Nc2ccc(CCC[PH](=O)O)cc2OC)ncc1C(F)(F)F
HCID178485570

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=O)c1nc(Br)ccc1Nc1nc(Nc2ccc(CCCC[PH](=O)O)cc2OC)ncc1C(F)(F)F
HCID178485566

未命名化合物

PROCEDURE

实验过程

Prepared analogously to Compound 67B replacing Compound 67C with ethyl (4-{[4-{[6-bromo-2-(methylcarbamoyl)pyridin-3-yl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-3-methoxybenzyl)propylphosphinate (Compound 74C). MS (ESI): m/z 617.55/619.52 [M+H]+. UPLC: tR=1.31 min (UPLC-SQD: analytical—2 min).

WORKUP

后处理

  1. customtR=1.31 min (UPLC-SQD: analytical—2 min)