Tetrahydrofuran → HCID 86707572, compound

Participants

Reaction Steps

2.60 g (4.20 mmol) 4″-(3-benzyloxy-propoxy)-3″-fluoro-5′-(2-methoxy-ethoxymethoxy)-4-(2-ethoxymethoxy-ethoxy)-[1,1′;3′,1″]terphenyl are hydrogenated in 50 ml THF on 1.0 g Pd/activated charcoal until the reaction is completed. The catalyst is filtered off and the solvent is removed in vacuo. 3-{3″-fluoro-5′-(2-methoxy-ethoxymethoxy)-4-[2-(2-methoxy-ethoxymethoxy)-ethoxy]-[1 1′;3′,1″]terphenyl-4″-yloxy}-propane-1-ol is obtained as colourless oil, which is used for the next step without further purification.

Provenance & Evidence