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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2279999Generated: October 30, 2026

Potassium Carbonate → HCID 58154169, compound

https://huagongshe.com/reaction/2279999

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2,4-Dichloro-5-nitropyrimidineHCID 521266—
ReactantHCID 57635047HCID 57635047—
SolventAcetoneHCID 180—
ProductHCID 58154169HCID 58154169—

Reaction Steps

Reaction of 1-cyclopentylaminomethyl-cyclopropanecarboxylic acid methyl ester with 2,4-dichloro-5-nitropyrimidine and K2CO3 in acetone gave 1-{[(2-Chloro-5-nitro-pyrimidin-4-yl)-cyclopentyl-amino]-methyl}cyclopropanecarboxylic acid ethyl ester. Treatment with NH4Cl and iron powder in ethanol gave 1-{[(5-Amino-2-chloro-pyrimidin-4-yl)-cyclopentyl-amino]-methyl}-cyclopropanecarboxylic acid ethyl ester

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133199B2
Source datasetuspto-grants-2015_09
ORD IDord-ea666ed3a3d5408194bed98caf8df647
Source noteuspto-grants-2015_09