HCID 86702667, compound → HCID 71729791, compound

HRID 2280059Notes

Reaction equation

HRID 2280059 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[CH2:10][CH2:11][CH2:12][C:13]#[C:14][P:15](=[O:22])([O:19][CH2:20][CH3:21])[O:16][CH2:17][CH3:18])=[CH:4][CH:3]=1>ClC1C=CC=CC=1Cl>[CH2:20]([O:19][P:15]([C:14]1[C:4]2[C:5](=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[CH:8]=[C:9]2[CH2:10][CH2:11][CH2:12][C:13]=12)(=[O:22])[O:16][CH2:17][CH3:18])[CH3:21]

Participants

3

Reactant 1

HCID 86702667HCID 86702667, compound

Product 1

HCID 71729791HCID 71729791, compound

Reagents, catalysts & solvents 1

HCID 72391,2-DichlorobenzeneSolvent

Conditions

Temperature
225 °C

Procedure

To a 0.5-2 mL microwave irradiation vial equipped with a stir bar was added enyne 5i (0.034 g, 0.10 mmol) in o-dichlorobenzene (1.7 mL). The reaction was irradiated with stirring at 225° C. for 150 min until complete by TLC. The reaction turned golden in color. The reaction was then transferred to a vial, concentrated under reduced pressure, and dried under vacuum to yield naphthalene 6i as an amber oil (0.034 g, quant.).

Workup

  1. customTo a 0.5-2 mL microwave irradiation
  2. customvial equipped with a stir bar
  3. customThe reaction was irradiated
  4. concentrationconcentrated under reduced pressure
  5. customdried under vacuum

Sources & evidence

ORD record
ord-80e4c344b807461d8e2fc81ed4362ced
Source dataset
uspto-grants-2015_09
Patent number
US09133234B2

Reaction notes

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