HCID 86702670, compound → HCID 86702669, compound

HRID 2280061Notes

Reaction equation

HRID 2280061 reaction equation
[C:1]1(/[CH:7]=[CH:8]/[CH2:9][CH2:10][CH2:11][C:12]#[C:13][C:14]([O:16][CH3:17])=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>ClC1C=CC=CC=1Cl>[CH2:9]1[C:8]2=[CH:7][C:1]3[C:6]([C:13]([C:14]([O:16][CH3:17])=[O:15])=[C:12]2[CH2:11][CH2:10]1)=[CH:5][CH:4]=[CH:3][CH:2]=3

Participants

3

Reactant 1

HCID 86702670HCID 86702670, compound

Product 1

HCID 86702669HCID 86702669, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 72391,2-DichlorobenzeneSolvent

Conditions

Temperature
225 °C

Procedure

To a 10-20 mL microwave irradiation vial equipped with a stir bar was added enyne 5k (0.150 g, 0.66 mmol) in o-dichlorobenzene (11 mL). The reaction was irradiated with stirring at 225° C. for 90 min until complete by TLC. The reaction turned golden in color. The reaction was then transferred to a vial and concentrated under high vacuum to yield naphthalene 6k as a black oil (0.144 g, 97%).

Workup

  1. customTo a 10-20 mL microwave irradiation
  2. customvial equipped with a stir bar
  3. customThe reaction was irradiated
  4. concentrationconcentrated under high vacuum

Sources & evidence

ORD record
ord-62a84fdf6c8a4d45a9fb0c72e97d25ef
Source dataset
uspto-grants-2015_09
Patent number
US09133234B2

Reaction notes

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