Ethyl acetate hexane → HCID 86702742, compound

Participants

Reaction Steps

To a 2-5 mL microwave irradiation vial equipped with a stir bar was added compound 4a (0.105 g, 0.30 mmol) in 1,2-dichlorobenzene (5 mL). The reaction was irradiated with stirring at 180° C. for 45 min until complete by TLC (AcOEt/n-hexane 3:7). The solution was directly added to a silica gel column, which was eluted with n-hexane to separate the 1,2-dichlorobenzene and then AcOEt/n-hexane 2:8 to collect the pure product. The title compound was isolated as a light yellow solid in an 85% yield (0.088 g).

Provenance & Evidence