Dimethylamine → HCID 72547092, compound

Participants

Reaction Conditions

Reaction Steps

Follows general procedure E: Ruphos palladacycle (2 mg, 0.0027 mmol), LHMDS (0.18 mL, 0.18 mmol), naphthalene (0.019 g, 0.088 mmol), THF (0.30 mL), and dimethylamine (0.13 mL, 0.26 mmol). The reaction mixture was heated at 85° C. for 1 h, turning the reaction mixture brown over time. The crude product was purified by silica gel flash column chromatography (1.5 cm, 10% ethyl acetate/hexanes) to yield the title compound as a light brown solid (5 mg, 25%).

Provenance & Evidence