HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroaniline → HCID 57756816, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroaniline | HCID 7240 | — |
| Reactant | (2S,4S)-1-[[N-(4-carboxybicyclo[2,2,2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile | HCID 57634365 | — |
| Product | HCID 57756816 | HCID 57756816 | — |
Reaction Steps
In a similar manner to Example 63, (2S,4S)-1-[[N-(4-carboxybicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (50.0 mg) and 2-chloroaniline (35.8 μL) were used to obtain (2S,4S)-1-[[N-[4-[N-(2-chlorophenyl)amino]carbonylbicyclo[2.2.2]oct-1-yl]amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (17.4 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560569B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-ac65ca6b9c524fdaacc7ddc3fe69ac29 |
| Source note | uspto-grants-2009_07 |