HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbamic acid, 4-pyridinyl-, 4-nitrophenyl ester → (S)-3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)-N-(pyridin-4-yl)piperidine-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbamic acid, 4-pyridinyl-, 4-nitrophenyl ester | HCID 10355188 | — |
| Reactant | (S)-3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidinium hydrochloride | HCID 86714280 | — |
| Product | (S)-3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)-N-(pyridin-4-yl)piperidine-1-carboxamide | HCID 73213662 | — |
Reaction Steps
Prepared as in Example 29 from 4-nitrophenyl pyridin-4-ylcarbamate (Example 28a) and (S)-3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidinium hydrochloride (Example 2a). MS=431 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09138013B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-8ca35868b24c41e8abddf06114db740f |
| Source note | uspto-grants-2015_09 |