HRID228023

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12007

2-Chloro-4-methylaniline

C7H8ClN

结构：N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2

HCID57634365

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(NC(=O)C23CCC(NCC(=O)N4C[C@@H](F)C[C@H]4C#N)(CC2)CC3)c(Cl)c1

HCID57756843

未命名化合物

PROCEDURE

实验过程

In a similar manner to Example 63, (2S,4S)-1-[[N-(4-carboxybicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (50.0 mg) and 2-chloro-4-methylaniline (41.8 μL) were used to obtain (2S,4S)-1-[[N-[4-[N-(2-chloro-4-methylphenyl)amino]carbonylbicyclo[2.2.2]oct-1-yl]amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (22.6 mg).