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HRID228029

反应详情

EQUATION

反应方程式

HRID 228029 的结构方程式

REACTANTS

反应物

2
结构：C=Cc1ccc(N)cc1
HCID73700

4-Vinylaniline

C8H9N

结构：N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2
HCID57634365

未命名化合物

PRODUCTS

生成物

1
结构：C=Cc1ccc(NC(=O)C23CCC(NCC(=O)N4C[C@@H](F)C[C@H]4C#N)(CC2)CC3)cc1
HCID57756787

未命名化合物

收率 20%

PROCEDURE

实验过程

In a similar manner to Example 63, (2S,4S)-1-[[N-(4-carboxybicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (50.0 mg) and 4-aminostyrene (46.0 mg) were used to obtain (2S,4S)-4-fluoro-1-[[N-[4-[N-(4-vinylphenyl)amino]carbonylbicyclo[2.2.2]oct-1-yl]amino]acetyl]pyrrolidine-2-carbonitrile (13.1 mg).