3-(Benzyloxycarbonylamino)propyl 2-acetoxybenzoate → 3-Aminopropyl 2-acetoxybenzoate

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Reaction Steps

A mixture of 3-(benzyloxycarbonylamino)propyl 2-acetoxybenzoate (2.0 g, 5.4 mmol), 10% Pd/C (0.2 g) and CH3OH (50 mL) was stirred under a H2 atmosphere (RT, 16 h). The mixture was filtered and concentrated under reduced pressure to afford a colorless oil. Purification by silica chromatography afforded 3-aminopropyl 2-acetoxybenzoate as a colorless oil. Mass calculated for C12H15NO4=237.25. found: [M+H]+=238.3.

Provenance & Evidence