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HRID228062

反应详情

EQUATION

反应方程式

HRID 228062 的结构方程式

REACTANTS

反应物

2
结构：Cl.NCC1CCCC1
HCID18784136

1-Cyclopentylmethanamine--hydrogen chloride (1/1)

C6H14ClN

结构：N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2
HCID57634365

未命名化合物

PRODUCTS

生成物

1
结构：N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)NCC3CCCC3)(CC1)CC2
HCID57756814

未命名化合物

收率 22.2%

PROCEDURE

实验过程

In a similar manner to Example 87, (2S,4S)-1-[[N-(4-carboxybicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (70.0 mg) and cyclopentylmethylamine hydrochloride (72.2 mg) were used to obtain (2S,4S)-1-[[N-[4-(N-cyclopentylmethylamino)carbonylbicyclo[2.2.2]oct-1-yl]amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (19.4 mg).