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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2280901Generated: October 29, 2026

1-Bromo-2-methylpropane → Tert-butyl 2-(2-((1-isobutylpiperidine-4-yl)(methyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamate

https://huagongshe.com/reaction/2280901

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-methylpropaneHCID 6555—
ReactantTert-butyl 4,6-dimethyl-2-(2-(methyl(piperidine-4-yl)amino)-2-oxoethoxy)pyrimidine-5-ylcarbamateHCID 59336171—
ProductTert-butyl 2-(2-((1-isobutylpiperidine-4-yl)(methyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamateHCID 68416124—

Reaction Steps

The title compound was synthesized from Compound 31 and isobutyl bromide in the same manner as in Example 32.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09139559B2
Source datasetuspto-grants-2015_09
ORD IDord-98b4a1a6fab747f98f1856ff133a3c07
Source noteuspto-grants-2015_09