1-benzyl-N-methylpiperidin-4-amine → HCID 59336190, compound
Reaction equation
[CH3:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[C:6]([CH3:11])[N:5]=[C:4]([NH:12][CH2:13][C:14]([OH:16])=O)[N:3]=1.[CH2:17]([N:24]1[CH2:29][CH2:28][CH:27]([NH:30][CH3:31])[CH2:26][CH2:25]1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([N:24]1[CH2:29][CH2:28][CH:27]([N:30]([CH3:31])[C:14](=[O:16])[CH2:13][NH:12][C:4]2[N:5]=[C:6]([CH3:11])[C:7]([N+:8]([O-:10])=[O:9])=[C:2]([CH3:1])[N:3]=2)[CH2:26][CH2:25]1)[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1Participants
3
Procedure
The title compound was synthesized from Compound 11 and 1-benzyl-N-methylpiperidine-4-amine in the same manner as in Example 49.
Sources & evidence
- ORD record
- ord-d85eeb7ae6df45efb0c24f94e3389466
- Source dataset
- uspto-grants-2015_09
- Patent number
- US09139559B2
Reaction notes
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