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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2280935Generated: October 26, 2026

1-(cyclopropylmethyl)-N-methylpiperidine-4-amine → 2-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylpropanamide

https://huagongshe.com/reaction/2280935

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(cyclopropylmethyl)-N-methylpiperidine-4-amineHCID 43314908—
Reactant2-(5-(Tert-butoxycarbonylamino)-4,6-dimethylpyrimidine-2-yloxy)propanoic acidHCID 59336093—
Product2-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylpropanamideHCID 59336143—

Reaction Steps

The title compound was synthesized from Compound 12 and 1-(cyclopropylmethyl)-N-methyl-piperidine-4-amine in the same manner as in Example 64.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09139559B2
Source datasetuspto-grants-2015_09
ORD IDord-d4f558012f954bb1b2b75660c526f349
Source noteuspto-grants-2015_09