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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2280941Generated: October 30, 2026

Maleic Acid → HCID 59336188, compound

https://huagongshe.com/reaction/2280941

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMaleic AcidHCID 444266—
ReactantHCID 59336094HCID 59336094—
ReactantHCID 59336188HCID 59336188—
SolventMethanolHCID 887—
ProductHCID 59336188HCID 59336188—
ProductHCID 68416174HCID 68416174—

Reaction Steps

2-(2-Amino-5-methylpyrimidine-4-ylamino)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide was synthesized from Compound 110 in the same manner as in Example 108. Then, to a methanol solution of 2-(2-amino-5-methylpyrimidine-4-ylamino)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide, 1 equivalent of maleic acid was added and the mixture was concentrated under reduced pressure to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09139559B2
Source datasetuspto-grants-2015_09
ORD IDord-47f6af56d8db423d956026b78477744a
Source noteuspto-grants-2015_09