HuagongsheHuagongshe Chemistry Print Report · For research reference only
Maleic Acid → HCID 59336188, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Maleic Acid | HCID 444266 | — |
| Reactant | HCID 59336094 | HCID 59336094 | — |
| Reactant | HCID 59336188 | HCID 59336188 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59336188 | HCID 59336188 | — |
| Product | HCID 68416174 | HCID 68416174 | — |
Reaction Steps
2-(2-Amino-5-methylpyrimidine-4-ylamino)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide was synthesized from Compound 110 in the same manner as in Example 108. Then, to a methanol solution of 2-(2-amino-5-methylpyrimidine-4-ylamino)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide, 1 equivalent of maleic acid was added and the mixture was concentrated under reduced pressure to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09139559B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-47f6af56d8db423d956026b78477744a |
| Source note | uspto-grants-2015_09 |