HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4S)-1-(tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid → 5-((4S)-4-phenylpyrrolidine-2-carboxamido)quinoline-8-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4S)-1-(tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid | HCID 20828633 | — |
| Reactant | 5-Amino-8-quinolinecarboxamide | HCID 89647225 | — |
| Product | 5-((4S)-4-phenylpyrrolidine-2-carboxamido)quinoline-8-carboxamide | HCID 89647105 | — |
Reaction Steps
The title compound was synthesized according to the procedure described for the preparation of Example 27 by using 5-aminoquinoline-8-carboxamide coupled with (4S)-1-(tert-butoxycarbonyl)-4-phenylpyrrolidine-2-carboxylic acid, followed by removal of the protecting group to afford Example 28. LC-MS. (M+H=361, obsd=361).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09139568B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-0607ed162809479b8c69e27c0c9eb8eb |
| Source note | uspto-grants-2015_09 |