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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2281019Generated: October 31, 2026

2-(((Tert-butoxy)carbonyl)amino)-2-phenylacetic acid → 5-(2-Amino-2-phenylacetamido)quinoline-8-carboxamide

https://huagongshe.com/reaction/2281019

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(((Tert-butoxy)carbonyl)amino)-2-phenylacetic acidHCID 571805—
Reactant5-Amino-8-quinolinecarboxamideHCID 89647225—
Product5-(2-Amino-2-phenylacetamido)quinoline-8-carboxamideHCID 89647638—

Reaction Steps

The title compound was synthesized according to the procedure described for the preparation of Example 27 by using 5-aminoquinoline-8-carboxamide coupled with 2-((tert-butoxycarbonyl)amino)-2-phenylacetic acid, followed by removal of the protecting group to afford Example 29. LC-MS (M+H=321, obsd=321).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09139568B2
Source datasetuspto-grants-2015_09
ORD IDord-2567fb4e124b4041aeeb24202703fa0b
Source noteuspto-grants-2015_09