2,4-Difluoronitrobenzene → HCID 117772721, compound

HRID 2281093Notes

Reaction equation

HRID 2281093 reaction equation
F[C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[N+:9]([O-])=O.[F:12][C:13]([F:23])([F:22])[CH:14]([C:16]1[O:20][N:19]=[C:18]([CH3:21])[CH:17]=1)[OH:15]>>[F:8][C:6]1[CH:5]=[CH:4][C:3]([NH2:9])=[C:2]([O:15][CH:14]([C:16]2[O:20][N:19]=[C:18]([CH3:21])[CH:17]=2)[C:13]([F:12])([F:23])[F:22])[CH:7]=1

Participants

3

Reactant 2

HCID 679672,4-DifluoronitrobenzeneHCID 117772618HCID 117772618, compound

Product 1

HCID 117772721HCID 117772721, compound

Procedure

Intermediate III.8 is prepared in a similar manner as intermediate III.4 from 2,4-difluoro-1-nitro-benzene and 2,2,2-trifluoro-1-(3-methylisoxazol-5-yl)ethanol.

Sources & evidence

ORD record
ord-44d319a643bf420aab1f5b8dc7c87c80
Source dataset
uspto-grants-2015_09
Patent number
US09139577B2

Reaction notes

Loading…