2,4-Difluoronitrobenzene → 3-(2-Amino-5-fluoro-phenoxy)-2-methyl-butan-2-ol

HRID 2281094Notes

Reaction equation

HRID 2281094 reaction equation
F[C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[N+:9]([O-])=O.[CH3:12][C:13]([OH:18])([CH:15]([OH:17])[CH3:16])[CH3:14]>>[NH2:9][C:3]1[CH:4]=[CH:5][C:6]([F:8])=[CH:7][C:2]=1[O:17][CH:15]([CH3:16])[C:13]([CH3:14])([OH:18])[CH3:12]

Participants

3

Reactant 2

HCID 679672,4-DifluoronitrobenzeneHCID 953622-Methylbutane-2,3-diol

Product 1

HCID 584134013-(2-Amino-5-fluoro-phenoxy)-2-methyl-butan-2-ol

Procedure

Is prepared in a similar manner as intermediate III.1 from 2,4-difluoro-1-nitro-benzene and 2-methylbutane-2,3-diol.

Sources & evidence

ORD record
ord-cd3e48b2aa214395b5f509385090913f
Source dataset
uspto-grants-2015_09
Patent number
US09139577B2

Reaction notes

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