2,4-Difluoronitrobenzene → HCID 117774614, compound

HRID 2281096Notes

Reaction equation

HRID 2281096 reaction equation
F[C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[N+:9]([O-])=O.[F:12][C:13]([F:18])([F:17])[C@H:14]([OH:16])[CH3:15]>>[F:8][C:6]1[CH:5]=[CH:4][C:3]([NH2:9])=[C:2]([O:16][C@H:14]([CH3:15])[C:13]([F:18])([F:17])[F:12])[CH:7]=1

Participants

3

Reactant 2

HCID 679672,4-DifluoronitrobenzeneHCID 6993809(2R)-1,1,1-trifluoropropan-2-ol

Product 1

HCID 117774614HCID 117774614, compound

Procedure

Is prepared in a similar manner as intermediate III.1 from 2,4-difluoro-1-nitro-benzene and (2R)-1,1,1-trifluoropropan-2-ol.

Sources & evidence

ORD record
ord-ecee0c8bfaff4b2da81a920a19f8607b
Source dataset
uspto-grants-2015_09
Patent number
US09139577B2

Reaction notes

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