2,4-Difluoronitrobenzene → HCID 117772140, compound

HRID 2281099Notes

Reaction equation

HRID 2281099 reaction equation
F[C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[N+:9]([O-])=O.C([O:19][CH2:20][C@@H:21]([OH:24])[CH2:22][F:23])C1C=CC=CC=1>>[NH2:9][C:3]1[CH:4]=[CH:5][C:6]([F:8])=[CH:7][C:2]=1[O:24][C@@H:21]([CH2:22][F:23])[CH2:20][OH:19]

Participants

3

Reactant 2

HCID 679672,4-DifluoronitrobenzeneHCID 100942919HCID 100942919, compound

Product 1

HCID 117772140HCID 117772140, compound

Procedure

Is prepared in a similar manner as intermediate III.1 from 2,4-difluoro-1-nitro-benzene and (2R)-1-benzyloxy-3-fluoro-propan-2-ol.

Sources & evidence

ORD record
ord-087bdc478c424a4890147c63378e7ebb
Source dataset
uspto-grants-2015_09
Patent number
US09139577B2

Reaction notes

Loading…