2,4-Difluoronitrobenzene → HCID 117772625, compound

HRID 2281100Notes

Reaction equation

HRID 2281100 reaction equation
F[C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[N+:9]([O-])=O.C([O:19][CH2:20][C@@H:21]([OH:26])[C:22]([F:25])([F:24])[F:23])C1C=CC=CC=1>>[NH2:9][C:3]1[CH:4]=[CH:5][C:6]([F:8])=[CH:7][C:2]=1[O:26][C@@H:21]([C:22]([F:25])([F:24])[F:23])[CH2:20][OH:19]

Participants

3

Reactant 2

HCID 679672,4-DifluoronitrobenzeneHCID 29933110HCID 29933110, compound

Product 1

HCID 117772625HCID 117772625, compound

Procedure

Is prepared in a similar manner as intermediate III.1 from 2,4-difluoro-1-nitro-benzene and (2R)-3-benzyloxy-1,1,1-trifluoro-propan-2-ol.

Sources & evidence

ORD record
ord-2904fbddb8f94722bd7516a77f7bfef1
Source dataset
uspto-grants-2015_09
Patent number
US09139577B2

Reaction notes

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