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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2281272Generated: November 1, 2026

HCID 68327758, compound → 2-(Quinuclidin-3-yl)acetic acid

https://huagongshe.com/reaction/2281272

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68327758HCID 68327758—
SolventHydrochloric AcidHCID 313—
Product2-(Quinuclidin-3-yl)acetic acidHCID 10352101—

Reaction Conditions

Temperature70 °C

Reaction Steps

A mixture of methyl 2-(quinuclidin-3-yl)acetate (1.1 g, 6.0 mmol) and 50 mL of conc. HCl [12M] was stirred at 70° C. for 18 h. The reaction mixture was concentrated under reduced pressure to afford crude 2-(quinuclidin-3-yl)acetic acid, which was used without purification in the next step (900 mg, 86%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09139580B2
Source datasetuspto-grants-2015_09
ORD IDord-0372c3ce848147c684507dea53ab015e
Source noteuspto-grants-2015_09