Thionyl Chloride → 3-(Propan-2-yl)benzoyl chloride

HRID 2281278Notes

Reaction equation

HRID 2281278 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7](O)=[O:8])([CH3:3])[CH3:2].O=S(Cl)[Cl:15]>>[CH:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][CH:12]=1)[C:7]([Cl:15])=[O:8])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 138552Benzoic acid, 3-(1-methylethyl)-

Product 1

HCID 222823793-(Propan-2-yl)benzoyl chlorideYield 91%

Conditions

Temperature
100 °C

Procedure

A mixture of 3-isopropyl-benzoic acid (5.00 g, 30.4 mmol) in SOCl2 (50 ml) was stirred at 100° C. for 2 h. The reaction mixture was concentrated to give 3-isopropyl-benzoyl chloride (5.00 g, 91%).

Workup

  1. concentrationThe reaction mixture was concentrated

Sources & evidence

ORD record
ord-ae91963b01c34499838d2db1944ba2ea
Source dataset
uspto-grants-2015_09
Patent number
US09139580B2

Reaction notes

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