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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2281310Generated: October 27, 2026

(3S)-6-bromo-3-methyl-3,4-dihydro-1H-isochromen-1-one → (3S)-3-Methyl-6-(oxiran-2-yl)-3,4-dihydro-1H-isochromen-1-one

https://huagongshe.com/reaction/2281310

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-6-bromo-3-methyl-3,4-dihydro-1H-isochromen-1-oneHCID 67517728—
Reactant(3R)-3-methyl-6-(oxiran-2-yl)-3,4-dihydro-1H-isochromen-1-oneHCID 86693039—
Product(3S)-3-Methyl-6-(oxiran-2-yl)-3,4-dihydro-1H-isochromen-1-oneHCID 86693038—

Reaction Steps

(3S)-3-Methyl-6-(oxiran-2-yl)-3,4-dihydro-1H-isochromen-1-one was prepared in an analogous fashion to that described for the synthesis of (3R)-3-methyl-6-(oxiran-2-yl)-3,4-dihydro-1H-isochromen-1-one except starting from (3S)-6-bromo-3-methyl-3,4-dihydro-1H-isochromen-1-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09139585B2
Source datasetuspto-grants-2015_09
ORD IDord-676caa7e0f4743198f07eac0e500946d
Source noteuspto-grants-2015_09