huagongshe.com
HRID2281327

反应详情

EQUATION

反应方程式

HRID 2281327 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1CN2
HCID11521263

(1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE

C10H18N2O2

结构：Cc1c([C@@H]2CO2)ccc2c1COC2=O
HCID59568646

4-Methyl-5-[(2R)-oxiran-2-yl]-2-benzofuran-1(3H)-one

C11H10O3

2 次

PRODUCTS

生成物

1
结构：Cc1c([C@@H](O)CN2C[C@@H]3C[C@H]2CN3)ccc2c1COC2=O
HCID117642045

未命名化合物

PROCEDURE

实验过程

5-{(1R)-2-[(1S,4S)-2,5-Diazabicyclo[2.2.1]hept-2-yl]-1-hydroxyethyl}-4-methyl-2-benzofuran-1 (3H)-one was prepared in an analogous fashion as described for the synthesis of INTERMEDIATE 3 starting from 4-methyl-5-[(2R)-oxiran-2-yl]-2-benzofuran-1 (3H)-one (INTERMEDIATE 2) and commercially available tert-butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate.