HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-3-pyridinecarbonitrile → HCID 71557027, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-3-pyridinecarbonitrile | HCID 5152094 | — |
| Reactant | HCID 117642214 | HCID 117642214 | — |
| Product | HCID 71557027 | HCID 71557027 | — |
Reaction Steps
(R)-6-(4-(2-Hydroxy-2-(4-methyl-1-oxo-1,3-dihydroisobenzofuran-5-yl)ethyl)piperazin-1-yl)nicotinonitrile was prepared in a similar fashion to that described for the synthesis of EXAMPLE 10 starting from (R)-5-(1-hydroxy-2-(piperazin-1-yl)ethyl)-4-methylisobenzofuran-1 (3H)-one hydrochloride (INTERMEDIATE 12) and 6-chloropyridine-3-carbonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09139585B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-dc81fcb468fd4373a2da5909b4b9479e |
| Source note | uspto-grants-2015_09 |