HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86636611, compound → HCID 44467019, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86636611 | HCID 86636611 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 44467019 | HCID 44467019 | 67.5% |
Reaction Steps
A solution of tert-butyl (1-(5-fluoro-2-(2-oxo-1,2,3,4-tetrahydroquinolin-6-ylamino)pyrimidin-4-yl)piperidin-4-yl)methylcarbamate (55 mg, 0.12 mmol) in TFA (3 mL) was stirred at room temperature for 60 min. TFA was removed in vacuo. The residue was purified by HPLC to give the titled compound (30 mg) MS 371.3 (M+H); UV 206.8, 274.8 nm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09139581B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-ceefacc9defb44499a76ae8b865ed87a |
| Source note | uspto-grants-2015_09 |