HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methylpyrimidine → cyclohexyl-[7-methyl-2-(1-methyl-1H-pyrrol-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methylpyrimidine | HCID 7939 | — |
| Reactant | 1-Methyl-1H-pyrrole-2-carbaldehyde | HCID 14504 | — |
| Reactant | Cyclohexyl isocyanide | HCID 79129 | — |
| Solvent | Perchloric Acid | HCID 24247 | — |
| Product | cyclohexyl-[7-methyl-2-(1-methyl-1H-pyrrol-2-yl)-imidazo[1,2-a]pyrimidin-3-yl]-amine | HCID 22591929 | — |
Reaction Steps
Compound (38) was prepared according to the general synthesis instructions from 1.0 ml of 2-amino-4-methylpyrimidine solution (0.1 M, DCM), 0.575 ml of cyclohexyl isocyanide solution (0.2 M, DCM), 0.500 ml of N-methylpyrrole-2-carbaldehyde solution (0.3 M, DCM), and 10 μl of perchloric acid (w=20%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06849642B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-9a13c14e378f4b7cabd9e4ac51904452 |
| Source note | uspto-grants-2005_02 |