Water → HCID 44467240, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of 2-(4-(4-acetylpiperazin-1-yl)phenylamino)-4-(4-(aminomethyl)piperidin-1-yl)pyrimidine-5-carboxamide (8 mg, 0.018 mmol) in CH3CN (1 mL), a solution of KCN (18 mg, 0.22 mmol) in H2O (1 mL) was added. The mixture was stirred at 70° C. for 20 h. It was then purified by HPLC to give the titled compound (6 mg). MS 496.5 (M+H); UV 200.8, 271.8 nm.

Provenance & Evidence