Trimethyl 4-bromoorthobutyrate → HCID 67087012, compound

HRID 2281638Notes

Reaction equation

HRID 2281638 reaction equation
O([CH2:8][CH2:9][N:10]1[C:18]2[CH:17]=[CH:16][CH:15]=[C:14]([C:19]([OH:21])=[O:20])[C:13]=2[CH:12]=[CH:11]1)C1C=CC=CC=1.[CH3:22][O:23][C:24]([O:31][CH3:32])([O:29][CH3:30])[CH2:25]CCBr>>[CH3:22][O:23][C:24]([O:31][CH3:32])([O:29][CH3:30])[CH2:25][CH2:8][CH2:9][N:10]1[C:18]2[CH:17]=[CH:16][CH:15]=[C:14]([C:19]([OH:21])=[O:20])[C:13]=2[CH:12]=[CH:11]1

Participants

3

Reactant 2

HCID 5187924Trimethyl 4-bromoorthobutyrateHCID 61677242HCID 61677242, compound

Product 1

HCID 67087012HCID 67087012, compound

Procedure

This compound is prepared analogously to Intermediate AO 1-(2-Phenoxy-ethyl)-1H-indole-4-carboxylic acid replacing (2-bromoethoxy)benzene with trimethyl 4-bromoorthobutyrate.

Sources & evidence

ORD record
ord-167917dc6de448ae9978e188b2eaf603
Source dataset
uspto-grants-2015_09
Patent number
US09139586B2

Reaction notes

Loading…