HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylpropyl isocyanate → 6-(3-Phenyl-propylcarbamoyl)-1,6-diaza-spiro[3.3]heptane-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylpropyl isocyanate | HCID 3427666 | — |
| Reactant | Tert-butyl 1,6-diazaspiro[3.3]heptane-1-carboxylate | HCID 56828076 | — |
| Product | 6-(3-Phenyl-propylcarbamoyl)-1,6-diaza-spiro[3.3]heptane-1-carboxylic acid tert-butyl ester | HCID 86682351 | — |
Reaction Steps
In analogy to the experimental procedure of example 8) 1,6-diaza-spiro[3.3]heptane-1-carboxylic acid tert-butyl ester instead of 1-benzyl-1,6-diaza-spiro[3.3]heptane was converted using (3-isocyanato-propyl)-benzene into the title compound which was used directly in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09139593B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-9381795e7854455da8dbd0d2d9a9c8c6 |
| Source note | uspto-grants-2015_09 |