HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Isocyanatoadamantane → 6-(Adamantan-1-ylcarbamoyl)-1,6-diaza-spiro[3.3]heptane-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Isocyanatoadamantane | HCID 2059995 | — |
| Reactant | Tert-butyl 1,6-diazaspiro[3.3]heptane-1-carboxylate | HCID 56828076 | — |
| Product | 6-(Adamantan-1-ylcarbamoyl)-1,6-diaza-spiro[3.3]heptane-1-carboxylic acid tert-butyl ester | HCID 86682352 | — |
Reaction Steps
In analogy to the experimental procedure of example 8) 1,6-diaza-spiro[3.3]heptane-1-carboxylic acid tert-butyl ester instead of 1-benzyl-1,6-diaza-spiro[3.3]heptane was converted using 1-isocyanato-adamantane instead of (3-isocyanato-propyl)-benzene into the title compound which was used directly in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09139593B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-809265d8ceda436aaf5e9fce6c4ad3a9 |
| Source note | uspto-grants-2015_09 |