HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → 3-Fluoro-4-(4-formylphenoxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3,4-Difluorobenzonitrile | HCID 587203 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Fluoro-4-(4-formylphenoxy)benzonitrile | HCID 53425670 | — |
Reaction Steps
Basic displacement reaction of 4-hydroxy benzaldehyde and 3,4 difluorobenzonitrile using potassium carbonate in anhydrous DMF at reflux temperatures affords the above compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560463B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-c02674a61c5f4a8580f06127af50fcf3 |
| Source note | uspto-grants-2009_07 |