N-Methylisobutylamine → HCID 43272232, compound

HRID 2281946Notes

Reaction equation

HRID 2281946 reaction equation
[CH3:1][NH:2][CH2:3][CH:4]([CH3:6])[CH3:5].N[CH2:8][C@@H:9]1CC[CH2:11][N:10]1CC>>[CH3:1][N:2]([CH2:3][CH:4]([CH3:6])[CH3:5])[CH2:8][CH2:9][NH:10][CH3:11]

Participants

3

Reactant 2

HCID 12249N-MethylisobutylamineHCID 643457(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine

Product 1

HCID 43272232HCID 43272232, compound

Procedure

By using N-methylisobutylamine (1.01 g) as a starting material, the title compound (170 mg) was obtained in the same manners as those of Reference Example 1, (1) and Reference Example 19, (3).

Sources & evidence

ORD record
ord-d38fd3e77c754ab9b0487614b9078bb1
Source dataset
uspto-grants-2015_09
Patent number
US09139609B2

Reaction notes

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