2-(Methylamino)ethanol → 2-{Methyl[2-(methylamino)ethyl]amino}ethan-1-ol

HRID 2281949Notes

Reaction equation

HRID 2281949 reaction equation
[CH3:1][NH:2][CH2:3][CH2:4][OH:5].N[CH2:7][C@@H:8]1CC[CH2:10][N:9]1CC>>[CH3:1][N:2]([CH2:7][CH2:8][NH:9][CH3:10])[CH2:3][CH2:4][OH:5]

Participants

3

Reactant 2

HCID 80162-(Methylamino)ethanolHCID 643457(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine

Product 1

HCID 149154782-{Methyl[2-(methylamino)ethyl]amino}ethan-1-ol

Procedure

By using 2-(methylamino)ethanol (867.5 mg) as a starting material, the title compound (740 mg) was obtained in the same manners as those of Reference Example 1, (1) and Reference Example 19, (3).

Sources & evidence

ORD record
ord-1f06853862c34c3dbdfbdb588a0ec361
Source dataset
uspto-grants-2015_09
Patent number
US09139609B2

Reaction notes

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