Acetaldehyde → HCID 89964233, compound

HRID 2281952Notes

Reaction equation

HRID 2281952 reaction equation
[CH3:1][O:2][CH2:3][C@H:4]1[CH2:8][CH2:7][CH2:6][NH:5]1.N[CH2:10][C@@H:11]1CC[CH2:13][N:12]1CC.C(=O)C>>[CH3:1][O:2][CH2:3][C@H:4]1[CH2:8][CH2:7][CH2:6][N:5]1[CH2:10][CH2:11][NH:12][CH3:13]

Participants

4

Reactant 3

HCID 177AcetaldehydeHCID 643457(S)-(-)-2-Aminomethyl-1-ethylpyrrolidineHCID 671216(2R)-2-(Methoxymethyl)pyrrolidine

Product 1

HCID 89964233HCID 89964233, compound

Procedure

By using O-methyl-D-prolinol (500 mg) as a starting material, the title compound (0.45 g) was obtained in the same manners as those of Reference Example 1, (1) and Reference Example 39, (2).

Sources & evidence

ORD record
ord-37b4ddd8fdb948749cd3021dd5a8537f
Source dataset
uspto-grants-2015_09
Patent number
US09139609B2

Reaction notes

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